THE SPECIFIC LOSS OF GNRH-POSITIVE NEURONS FROM THE HYPOTHALAMUS OF SHEEP WITH CLN6 NEURONAL CEROID LIPOFUSCINOSIS OCCURS WITHOUT GLIAL ACTIVATION AND HAS ONLY MINOR EFFECTS ON REPRODUCTION

The specific loss of GnRH-positive neurons from the hypothalamus of sheep with CLN6 neuronal ceroid lipofuscinosis occurs without glial activation and has only minor effects on reproduction

The neuronal ceroid lipofuscinoses (NCLs, Batten disease) are characterized by progressive neurodegeneration resulting in widespread brain atrophy.Each form is assumed to be the consequence of some universal intracellular event; however, time course studies on the cerebral cortex of a sheep model of the CLN6 form revealed distinct regional neurodeg

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The impact and management of internet-based public opinion dissemination during emergencies: A case study of Baidu News during the first wave of coronavirus disease 2019 (COVID-19).

Background and aimsThe coronavirus disease Music Fridge Magnet 2019 (COVID-19) public health emergency has had a huge impact worldwide.We analyzed news headlines and keywords from the initial period of COVID-19, and explored the dissemination timeline of news related to the epidemic, and the impact of Internet-based media on the public using lifecy

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Differential expression of genes identified from Poncirus trifoliata tissue inoculated with CTV through EST analysis and in silico hybridization

Citrus is the most important fruit crop in Brazil and Citrus tristeza virus (CTV) is considered one of the most important pathogens of citrus.Most citrus species and varieties are susceptible to CTV infection.However, Poncirus trifoliata, a close relative of citrus, is resistant to the virus.In order to better understand the responses of Staple Car

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